BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residue and a propeptide of 110 amino acid residues. Recombinant human BDNF is a 27.0 kDa homodimer of two 120 amino acid subunits linked by strong non-covalent interactions. Human and Mouse BDNF sequences are identical.Manufactured using all non-animal reagents.
Biogems为PeproTech公司推出自己的流式细胞术产品品牌, BioGems意为生物之珠宝。
其产品涵盖多种荧光标记的流式抗体、具有生物活性的功能性抗体,以及流式细胞术辅助试剂,如溶血剂和破膜剂等。
BioGems产品全部在美国生产,相信其优异的品质和低于其它国际流式厂商的价位将能为广大用户提供更好的选择。