Description
The HM47 monoclonal antibody reacts with the cytoplasmic domain of CD79a, a 47kDa type I integral membrane protein known as Iga or mb-1. It forms the part of the B-cell receptor complex with CD79b and is expressed on B cells from earliest pre-B to plasma cell stage. It is also reported that CD79a expresses weakly on myeloid cells and T cell precursors. CD79a is believed to be involved in transporting IgM to the surface of B cells.