Description
CTACK is a keratinocyte-derived CC chemokine which signals through the CCR10 receptor.Both CTACK and CCR10 are expressed in normal and irritated epithelial cells.CTACK selectively attracts CLA+ T-cells and directs them into the skin.CTACK contains the four highly conserved cysteine residues present in most CC chemokines.The mature protein contains 88 amino acid residues.Recombinant human CTACK is a 10.2 kDa protein containing 88 amino acid residues.